I'm pleased to announce the publication of "Cholesterol and PI(4,5)P2 in Vital Biological Functions: From Coexistence to Crosstalk" edited by Avia Rosenhouse-Dantsker. Yuanyuan and I contributed a chapter entitled, "Mechanism of the regulation of plasma cholesterol levels by PI(4,5)P2".
This book provides an overview of cellular functions and molecular mechanisms in which cholesterol and PI(4,5)P2 functions extend from parallel existence to crosstalk. It includes four sections. The first section introduces the reader to cholesterol and PI(4,5)P2. The second section demonstrates the mutual influence of these two critical lipids on their levels. The third section, divided into two parts, describes the co-modulation of protein function by cholesterol and PI(4,5)P2. The first part focuses on ion channels and the second - on lipid transfer proteins. The fourth section highlights other cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement. Collectively, the book portrays the emerging relationship between cholesterol and PI(4,5)P2 in a broad array of biological systems and processes.
If interested, you can find the book at either Barnes and Nobles or Amazon.
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